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Does hydroxychloroquine suppress the immune system?
Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. It is believed that hydroxychloroquine interferes with the communication of cells in the immune system.
What causes splenomegaly in malaria?
cause of spleen rupture and splenomegaly. Spleen is the main organ that generates the immune response to the malaria parasite and controls the removal of the infected red blood cells, as a result of which reticuloendothelial system is activated that causes enlargement of the spleen.
What happens if malaria is left untreated?
Malaria is a disease caused by parasites that are transmitted to people by certain types of mosquitoes. Malaria parasites live in red blood cells and can cause fever, headache, vomiting and convulsions. If left untreated, malaria can lead to severe illness and death.
What are the side effect of artemether?
Nervous system side effects have included headache, dizziness, and vertigo (3% or more). Tinnitus, ataxia, clonus, fine motor delay, hyperreflexia, hypoesthesia, nystagmus, and tremor have been reported in less than 3% of patients. Ototoxicity (including decreased hearing) and paresthesia have been reported.
What is the most effective antimalarial drug?
A combination of antimalarial medications called chloroquine and proguanil is also available, although these are rarely recommended nowadays because they're largely ineffective against the most common and dangerous type of malaria parasite, Plasmodium falciparum.
What is the method of transmission of malaria?
Mode of Transmission : Malaria is transmitted by the bite of an infective female Anopheles mosquito. Transfusion of blood from infected persons and use of contaminated needles and syringes are other potential modes of transmission. Congenital transmission of malaria may also occur.
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